关于the Report
本报告利用IQVIA基因组计划数据库（一个新的基因组数据计划数据库）来检查和分割全球基因组局势。在Covid-19时代，基因组数据库发挥的作用正在增长。例如，英国生物银行和芬根（Finngen）等人目前正在努力了解患者对Covid-19的遗传决定因素以及对感染的严重反应。1,2他们还与COVID-19主机遗传学计划合作3帮助共同研究人员在全球生成，共享和分析数据。基因组数据计划的第一个景观的发布提供了有关人类基因组数据的重要用途的基准，这是衡量进步的洞察力，以衡量对人类疾病起源的洞察力并开发更好的治疗剂来预防和治疗疾病。有了它，利益相关者可以更好地了解当前的基因组景观。
报告摘要
The landscape of initiatives to generate and collect human genomic data is evolving rapidly and is highly diverse, with private and public initiatives across multiple countries. Since 1990, the cost of sequencing a whole genome dropped from $2.7 million to as low as $300, opening new opportunities to build repositories of genomic data. By the start of 2020, there were 187 genomic initiatives globally of which 50% originated in the U.S. and 19% in Europe. Thirty-eight million genomes had been analyzed using techniques ranging from genotyping to whole genome sequencing, and this number is expected to grow to 52 million by 2025.
随着各国越来越多地欣赏基因组数据的潜在技术和医疗保健系统的好处，计划中的国家基因组数据库正在扩大，其中一些国家计划对其整个人群进行排序。必威手机APP数据的医疗效用是根据收集的基因组数量，基因组数据的完整性，与其他医疗保健相关的数据及其涵盖的疾病或人群的完整性，基因组数据的完整性，与其他疾病或人群的联系而有所不同。必威手机APPAlthough only 42% of databases publicly state their genomic data links to patient demographic information or clinical data and only 28% state links to the most valuable EMR/EHR and clinical data, an analysis of initiatives’ data quality versus their target cohort sizes suggests that the next decade will see an increasing number of large genomic databases with strong utility for human data science and medical research.
1Morelle R. UK Biobank：DNA解锁冠状病毒秘密。英国广播公司的新闻。2020年4月14日。可从：https://www.bbc.com/news/必威手机APPhealth-52243605
2Finngen. Finngen involved in the Covid19 study. Accessed May 4, 2020. Available from:https://www.finngen.fi/fi/finngen_mukana_covid19_tutkimuksessa
3COVID-19-BOST遗传学计划。可从：https://www.covid19hg.org/
